| Date | Time | Match-up | Money Line | Spread | Total |
| 2022-08-03 | 20:00 | New York Giants Buffalo Bills | OFF | +1 -107 / 1.93 -1 -107 / 1.93 | Over 32.5 -107 / 1.93 Under 32.5 -107 / 1.93 |
| 2022-09-04 | 20:30 | Green Bay Packers Seattle Seahawks | OFF | +5.5 -107 / 1.93 -5.5 -107 / 1.93 | Over 44.5 -107 / 1.93 Under 44.5 -107 / 1.93 |
| 2022-09-07 | 13:00 | New Orleans Saints Atlanta Falcons | OFF | +1.5 -107 / 1.93 -1.5 -107 / 1.93 | Over 52 -107 / 1.93 Under 52 -107 / 1.93 |
| 2022-09-07 | 13:00 | Minnesota Vikings St. Louis Rams | OFF | +6 -107 / 1.93 -6 -107 / 1.93 | Over 45.5 -107 / 1.93 Under 45.5 -107 / 1.93 |
| 2022-09-07 | 13:00 | Cleveland Browns Pittsburgh Steelers | OFF | +6 -107 / 1.93 -6 -107 / 1.93 | Over 40 -107 / 1.93 Under 40 -107 / 1.93 |
| 2022-09-07 | 13:00 | Jacksonville Jaguars Philadelphia Eagles | OFF | +11 -107 / 1.93 -11 -107 / 1.93 | Over 51.5 -107 / 1.93 Under 51.5 -107 / 1.93 |
| 2022-09-07 | 13:00 | Oakland Raiders New York Jets | OFF | +4.5 -105 / 1.95 -4.5 -115 / 1.87 | Over 40 -107 / 1.93 Under 40 -107 / 1.93 |
| 2022-09-07 | 13:00 | Cincinnati Bengals Baltimore Ravens | OFF | +2 -107 / 1.93 -2 -107 / 1.93 | Over 43 -107 / 1.93 Under 43 -107 / 1.93 |
| 2022-09-07 | 13:00 | Buffalo Bills Chicago Bears | OFF | +6 -107 / 1.93 -6 -107 / 1.93 | Over 48.5 -107 / 1.93 Under 48.5 -107 / 1.93 |
| 2022-09-07 | 13:00 | Washington Redskins Houston Texans | OFF | +2.5 100 / 2.00 -2.5 -120 / 1.83 | Over 45 -107 / 1.93 Under 45 -107 / 1.93 |
| 2022-09-07 | 13:00 | Tennessee Titans Kansas City Chiefs | OFF | +6 -107 / 1.93 -6 -107 / 1.93 | Over 44 -107 / 1.93 Under 44 -107 / 1.93 |
| 2022-09-07 | 13:00 | New England Patriots Miami Dolphins | OFF | -4 -107 / 1.93 +4 -107 / 1.93 | Over 47 -107 / 1.93 Under 47 -107 / 1.93 |
| 2022-09-07 | 16:25 | Carolina Panthers Tampa Bay Buccaneers | OFF | OFF | Over 39.5 -107 / 1.93 Under 39.5 -107 / 1.93 |
| 2022-09-07 | 16:25 | San Francisco 49ers Dallas Cowboys | OFF | -4.5 -115 / 1.87 +4.5 -105 / 1.95 | Over 48.5 -107 / 1.93 Under 48.5 -107 / 1.93 |
| 2022-09-07 | 20:30 | Indianapolis Colts Denver Broncos | OFF | +6.5 -105 / 1.95 -6.5 -115 / 1.87 | Over 55 -107 / 1.93 Under 55 -107 / 1.93 |
| 2022-09-08 | 19:10 | New York Giants Detroit Lions | OFF | +4 -107 / 1.93 -4 -107 / 1.93 | Over 45.5 -107 / 1.93 Under 45.5 -107 / 1.93 |
| 2022-09-08 | 22:20 | San Diego Chargers Arizona Cardinals | OFF | +3.5 -107 / 1.93 -3.5 -107 / 1.93 | Over 44.5 -107 / 1.93 Under 44.5 -107 / 1.93 |